Drug Metabolism

Approximately one out of every 1,000 compounds identified in preclinical studies is eventually found suitable for human use. This creates a need to shorten the time and cost to increase the "hit" rate of finding drug candidates. This course will give you a comprehensive understanding of the biochemical aspects of drug metabolism in the drug discovery process and related pharmaceutical principles. Topics include pharmacokinetics, Phase I and II drug metabolism, factors affecting drug metabolism, and recent advances in drug metabolizing and absorption technology. The goal of this course is to give students a full appreciation of the drug metabolism aspects of the NDA process as well as an ability to predict drug metabolism and distribution of new chemical entities.

Course Number: BIOL-40170   Credit: 3 units

This course is part of the following Certificate Program(s):

• ADMET Process

• Drug Discovery and Development