This course provides a fundamental overview and introduction to classical organic chemistry. Students will gain a general understanding of chemical structure representation, Lewis dot structures, formal charges, lone pairs, atom hybridization, bond geometry and resonance structures. There is an emphasis on stereochemistry and three-dimensional structure representation: Newman and Fischer Projections, R- and S- nomenclature.
The first half of the course will provide an introduction of chemical reactivity and reaction mechanisms starting with nucleophilic substitution and elimination reactions, followed by more focused overview of various classes of organic compounds and their chemical reactivity: alkenes, alkynes, alcohols and their derivatives – ethers and epoxides.
The second half of the course focuses on the concept of aromaticity and chemical properties of aromatic compounds, followed by an introduction to the chemical reactivity of compounds containing carbonyl groups and their derivatives: ketones and aldehydes, carboxylic acids, acid halides, esters, nitriles and amides, enols and enolates. Students should become familiar with the chemistry of amines as well as learn about several classic named reactions and their mechanisms, such as: the Friedel-Crafts acylation and alkylation, the Grignard and the Baeyer-Villiger reactions, the Michael addition, the Wittig reaction, and the Diels-Alder cycloaddition.
This course is designed for biology, premedical, prenursing, preclinical, prehealth students and anyone who is interested in learning introductory organic chemistry. A foundation in general chemistry is preferred to understand the topics of this course.
Course Number: CHEM-40010
Credit: 4.50 unit(s)
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6/21/2021 - 9/4/2021
9/20/2021 - 12/4/2021