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Gain a comprehensive understanding of preclinical drug discovery and development.  Through the use of lectures, case studies and discussion, this course will cover the framework of the various stages of developing a therapeutic agent including biologics.  This course is appropriate for those without a strong technical background as well as experienced biologists and chemists, who want to gain knowledge into how new drugs are discovered and the processes needed to take them to clinical studies.

Topics include:

  • Drug targets, mechanisms and target identification

  • Target based drug design and modeling

  • Lead generation and optimization

  • Cell and animal experimentation

  • ADME

  • Pharmacokinetics and Pharmacodynamics

  • Toxicity, drug safety pharmacology

  • Biologic drugs

  • Formulations

  • Investigational New Drug (IND) filings.

Learning Objectives:

  • Understand the different stages of the process of drug discovery and development

  • Identify the role played by different disciplines in preclinical drug development

  • Appreciate the interplay between business and science in drug discovery

  • Be aware of the legal regulations to be thought through to get a drug commercialized

  • Analyze case studies that exemplify the modern drug discovery and preclinical processes


  • COURSE NUMBER  BIOL-40125
  • CREDIT  3.00 unit(s)


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